Catalytic peptide assemblies,Chemical Society Reviews

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Catalytic peptide assemblies
Chemical Society Reviews ( IF 40.4 ) Pub Date : 2018-03-29 00:00:00 , DOI: 10.1039/c8cs00080h
O Zozulia ₁ , M A Dolan , I V Korendovych

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Self-assembly of molecules often results in new emerging properties. Even very short peptides can self-assemble into structures with a variety of physical and structural characteristics. Remarkably, many peptide assemblies show high catalytic activity in model reactions reaching efficiencies comparable to those found in natural enzymes by weight. In this review, we discuss different strategies used to rationally develop self-assembled peptide catalysts with natural and unnatural backbones as well as with metal-containing cofactors.

中文翻译：

催化肽组装体

分子的自组装通常会产生新的特性。即使非常短的肽也可以自组装成具有各种物理和结构特征的结构。值得注意的是，许多肽组装体在模型反应中表现出高催化活性，其效率与按重量计算的天然酶中的效率相当。在这篇综述中，我们讨论了用于合理开发具有天然和非天然主链以及含金属辅因子的自组装肽催化剂的不同策略。

更新日期：2018-03-29

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