Fabrication and evaluation of hemoglobin-based polydopamine microcapsules as oxygen carriers†,Chemical Communications

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Fabrication and evaluation of hemoglobin-based polydopamine microcapsules as oxygen carriers†
Chemical Communications ( IF 4.9 ) Pub Date : 2018-03-29 00:00:00 , DOI: 10.1039/c8cc00095f
Chunmei Yu _{1,

2,

3,

4} , Xin Huang _{1,

2,

3,

4} , Dongping Qian _{1,

2,

3,

4} , Fengfeng Han _{1,

2,

3,

4} , Linyi Xu _{1,

2,

3,

4} , Yuejing Tang _{1,

2,

3,

4} , Ning Bao _{1,

2,

3,

4} , Haiying Gu _{1,

2,

3,

4}

Affiliation

Polydopamine-hemoglobin (PDA-Hb) microcapsules as suitable oxygen carriers are fabricated easily by templating decomposable MnCO₃ particles in collaboration with self-polymerization of dopamine on pure Hb spheres. The PDA-Hb microcapsules possess a high oxygen affinity and are able to bind and release oxygen reversibly as demonstrated by electrochemical methods.

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