An efficient synthesis of 1,2,4-oxadiazinan-5-ones via [3+3] cycloaddition of in situ generated aza-oxyallyl cations with nitrones has been developed. The protocol features easy operation, excellent yields, excellent diastereo-control, broad substrate scope and good functional group tolerance.

中文翻译：

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氮杂-氧烯丙基阳离子和硝酮的高度非对映选择性[3 + 3]环化反应

通过原位生成的氮杂-氮烯丙基阳离子与硝酮的[3 + 3]环加成反应，已开发出有效合成1,2,4-氧杂二氮杂-5-酮的方法。该协议具有易于操作，优异的产率，出色的非对映控制，广泛的底物范围和良好的官能团耐受性等特点。