Assembling the Puzzle of Apixaban Solid Forms,Molecular Pharmaceutics

当前位置： X-MOL 学术 › Mol. Pharmaceutics › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Assembling the Puzzle of Apixaban Solid Forms
Molecular Pharmaceutics ( IF 4.5 ) Pub Date : 2018-03-27 00:00:00 , DOI: 10.1021/acs.molpharmaceut.8b00060
Rafael Barbas ₁ , Cristina Puigjaner ₁ , Rafel Prohens ₁

Affiliation

An in-depth analysis of the solid forms of the anticoagulant drug Apixaban (APX) has been conducted to sort out the confusion in the scientific and patent literature regarding the solid forms landscape. The nomenclature employed and the accompanying characterization data are often unclear and incomplete, leading to a situation in which apparently the same form has been reported by different authors or claimed by different inventors. A comprehensive solid forms screen and a full and careful comparison with the literature data has been performed to draw a reliable picture of the solid forms landscape of APX.

中文翻译：

组装Apixaban固体形式的难题

已经对抗凝药物阿哌沙班（APX）的固体形式进行了深入分析，以理清有关固体形式前景的科学和专利文献中的混淆。所采用的术语和随附的表征数据通常不清楚且不完整，导致出现这样的情况，即不同作者显然已经报告了相同的形式，或者不同的发明者要求了相同的形式。进行了全面的实体表格屏幕，并与文献数据进行了全面而仔细的比较，以绘制出APX实体表格景观的可靠图片。

更新日期：2018-03-27

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11