Despite their high global incidence, sexually transmitted infections (STIs) remain a neglected area of research. Increased rates of STIs have been reported in particular among men who have sex with men (MSM) probably because of the advances in the treatment and prophylaxis of human immunodeficiency virus (HIV) infection with a decrease in condom use. A recent report among MSM showed that the use of postexposure prophylaxis with doxycycline could dramatically reduce the incidence of chlamydia and syphilis but not of gonorrhea. The long-term consequences of this strategy are yet unknown, especially the risk of selection and dissemination of syphilis and chlamydia strains with doxycycline resistance, which has not been reported yet.

中文翻译：

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强力霉素对细菌性传播感染的预防：承诺和风险。

尽管全球性发病率很高，但性传播感染（STIs）仍然是研究领域中被忽略的领域。据报道，特别是在与男性发生性关系（MSM）的男性中，性传播感染的发生率增加，可能是由于治疗和预防人类免疫缺陷病毒（HIV）感染的进展以及避孕套使用的减少。MSM中的最新报告表明，用强力霉素进行暴露后预防可显着降低衣原体和梅毒的发生率，但不会减少淋病。该策略的长期后果尚不清楚，尤其是选择和传播具有强力霉素抗性的梅毒和衣原体菌株的风险，尚未见报道。