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Photo-antimicrobial efficacy of zinc complexes of porphyrin and phthalocyanine activated by inexpensive consumer LED lamp
Journal of Inorganic Biochemistry ( IF 3.9 ) Pub Date : 2018-03-24 , DOI: 10.1016/j.jinorgbio.2018.03.015
Lijo George , Arto Hiltunen , Ville Santala , Alexander Efimov

The properties and antimicrobial efficacies of zinc complexes of tetrakis(N-methylpyridinium-4-yl) tetraiodide porphyrin and tetrakis(N-methylpyridinium-4-yl) tetraiodide phthalocyanine impregnated to paper were evaluated. Photo-inactivation of microbes using inexpensive consumer light-emitting diode lamp was assessed on surface of dyed papers. Antimicrobial experiments of phthalocyanine-dyed paper by live cell assessment through colony forming units counting demonstrated 3.72 and 4.01 log reduction against Escherichia coli (E. coli) and Acinetobacter baylyi (A. baylyi) respectively after 1 h of illumination with 35 mW/cm2 light. The porphyrin-dyed paper exhibited 1.66 and 2.01 log reduction in colony forming units against E. coli and A. baylyi respectively after 1 h exposure with 4 mW/cm2 light. Both dyed papers were photo-stable after 64 h of continuous exposure with 42 mW/cm2 light, while phthalocyanine-dyed paper exhibited superior leaching stability in phosphate-buffered saline.



中文翻译:

廉价的消费型LED灯激活的卟啉和酞菁锌配合物的光抗菌作用

对四(N-甲基吡啶-4-基)四碘卟啉和四(N-甲基吡啶-4-基)四碘酞菁浸渍纸的锌配合物的性质和抗菌性能进行了评价。使用廉价的消费性发光二极管灯在染色纸的表面上评估了微生物的光灭活。通过菌落形成单位计数通过活细胞评估酞菁染色纸的抗菌实验表明,在35 mW / cm 2的光照下1 h,分别对大肠杆菌E. coli)和拜氏不动杆菌A. baylyi)的对数减少3.72和4.01 log光。在用4 mW / cm 2的光照射1 h后,用卟啉染色的纸分别对大肠杆菌Baylyi菌落的菌落形成单位分别降低了1.66和2.01 log 。两种染色的纸在42 mW / cm 2的光下连续曝光64 h后都具有光稳定性,而酞菁染色的纸在磷酸盐缓冲液中显示出优异的浸出稳定性。

更新日期:2018-03-24
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