Food and Chemical Toxicology ( IF 3.9 ) Pub Date : 2018-03-21 , DOI: 10.1016/j.fct.2018.03.028 Alexsandro Dallegrave , Tânia M. Pizzolato , Fabiano Barreto , Vinicius C. Bica , Ethel Eljarrat , Damià Barceló
The goal of this work is to study the presence of 17 different pyrethroids and chlorpyrifos in animal origin food samples, including chicken, beef, fish, eggs and milk. The samples were analyzed by GC/NCI-MS/MS in order to determine their insecticide concentration levels, the relation between the amount of insecticides and the lipid content, as well as their isomeric composition. Bifenthrin, cypermethrin, cyhalothrin, permethrin, deltamethrin and chlorpyrifos have been detected in real samples. The highest levels find were verified for chlorpyrifos (45.7 μg L−1, 17.5 μg kg−1 ww) and cypermethrin (2.75 μg L−1, 14.7 μg kg−1 ww) in milk and beef, respectively. The estimate of daily intake showed that none of these insecticides exceeded the safety limits of the acceptable daily intake values. A strong correlation between the amount of pesticides and lipid content was found for beef, fish and chicken samples. Regarding the isomers, a predominance of cis isomers in samples contaminated with cypermethrin was verified.
中文翻译:
食品中杀虫剂的残留和巴西公民的饮食暴露评估
这项工作的目的是研究动物源性食物样品中存在17种不同的拟除虫菊酯和毒死rif,其中包括鸡肉,牛肉,鱼,蛋和牛奶。通过GC / NCI-MS / MS分析样品,以确定其杀虫剂浓度水平,杀虫剂数量与脂质含量之间的关系以及它们的异构体组成。在真实样品中已检测到联苯菊酯,氯氰菊酯,氯氟氰菊酯,氯菊酯,溴氰菊酯和毒死rif。最高级别的发现证实了毒死蜱(45.7微克大号-1,17.5微克千克-1湿重)和氯氰菊酯(2.75微克大号-1,14.7微克公斤-1ww)分别在牛奶和牛肉中。每日摄入量的估算表明,这些杀虫剂均未超过可接受的每日摄入量值的安全极限。牛肉,鱼和鸡肉样品中的农药含量与脂质含量之间存在很强的相关性。关于异构体,证实了在氯氰菊酯污染的样品中主要存在顺式异构体。