I read the interesting study entitled ‘Relationship between serum urate concentration and clinically evident incident gout: an individual participant data analysis’ conducted by Dalbeth and colleagues.1 Their study showed the cumulative incidence of gout was increased with the serum urate levels and the cumulative years. The reference level of serum urate below which the risk of damage is low has not been completely clarified. The benchmark dose (BMD) method, first described by Crump in 1984,2 has been widely used in the field …

中文翻译：

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临床明显痛风的血清尿酸参考水平

我阅读了 Dalbeth 及其同事进行的题为“血清尿酸浓度与临床明显痛风事件的关系：个体参与者数据分析”的有趣研究。1 他们的研究表明，痛风的累积发病率随着血清尿酸水平和累积年数而增加. 低于该参考水平的血清尿酸损害风险较低，尚未完全阐明。基准剂量 (BMD) 方法由 Crump 在 1984 年首次描述，2 已广泛应用于该领域……