From the interplay of high-resolution scanning tunneling microscopy imaging and density functional theory calculations, we show the real-space evidence of the formation of Watson–Crick and Hoogsteen adenine–uracil base pairs on an Au(111) surface with the employment of base derivatives, and further investigate the relative stability of the two types of adenine–uracil base pairs.

中文翻译：

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Au（111）上的Watson-Crick和Hoogsteen腺嘌呤-尿嘧啶碱基对的真实空间证据†

从高分辨率扫描隧道显微镜成像和密度泛函理论计算的相互作用，我们显示了利用碱在Au（111）表面上形成Watson-Crick和Hoogsteen腺嘌呤-尿嘧啶碱基对的真实空间证据。衍生物，并进一步研究两种类型的腺嘌呤-尿嘧啶碱基对的相对稳定性。