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A supramolecular self-assembly strategy for upconversion nanoparticle bioconjugation†
Chemical Communications ( IF 4.9 ) Pub Date : 2018-03-19 00:00:00 , DOI: 10.1039/c8cc00708j
Yulong Sun 1, 2, 3, 4, 5 , Wenjing Zhang 1, 2, 3, 4, 5 , Baoming Wang 1, 2, 3, 4, 5 , Xiaoxue Xu 1, 2, 3, 4, 5 , Joshua Chou 2, 3, 4, 6, 7 , Olga Shimoni 1, 2, 3, 4, 5 , Alison T. Ung 2, 3, 4, 8, 9 , Dayong Jin 1, 2, 3, 4, 5
Affiliation  

An efficient surface modification for upconversion nanoparticles (UCNPs) is reported via supramolecular host–guest self-assembly. Cucurbit[7]uril (CB) can provide a hydrophilic surface and cavities for most biomolecules. High biological efficiency, activity and versatility of the approach enable UCNPs to be significantly applied in bio-imaging, early disease detection, and bio-sensing.

中文翻译:

上转换纳米粒子生物共轭的超分子自组装策略

据报道,通过超分子宿主客体自组装,可以对上转换纳米粒子(UCNPs)进行有效的表面修饰。葫芦[7]尿素(CB)可以为大多数生物分子提供亲水性表面和空腔。该方法的高生物效率,活性和多功能性使UCNPs可以显着应用于生物成像,疾病早期检测和生物传感。
更新日期:2018-03-19
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