Atherosclerosis, a lipid-driven chronic inflammatory artery disease, has been recognized as the main pathology underlying cardiovascular disease (CVD) and as the leading cause of death worldwide. Early identification of individuals at high risk of CVD is fundamental to tailor targeted treatment and especially prevention strategies. This mandates an ongoing need to identify biological markers that are useful to stratify CVD risk.

中文翻译：

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动脉粥样硬化斑块的代谢组学分析：改善心血管风险分层

动脉粥样硬化是一种脂质驱动的慢性炎症性动脉疾病，已被公认为心血管疾病 (CVD) 的主要病理学类型，也是全球主要的死亡原因。早期识别 CVD 高风险个体对于定制针对性治疗尤其是预防策略至关重要。这要求不断需要确定有助于对 CVD 风险进行分层的生物标志物。