当前位置: X-MOL 学术Tetrahedron Lett. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Concise total synthesis of AB5046A and AB5046B
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2018-03-17 , DOI: 10.1016/j.tetlet.2018.03.038
Lu-Yao Kong , Qing Cui , Zhong Jin , Xiao-Hua Xu

Two naturally occurring rare 5-oxo β-triketones, AB5046A and AB5046B, were efficiently synthesized in five linear steps with overall yields of 36% and 28%, respectively. The synthetic strategy highlighted the readily preparation of the key intermediate, 3-ethoxy-5-hydroxycyclohex-2-enone, from commercially available phloroglucinol.



中文翻译:

AB5046A和AB5046B的简明全合成

两个天然存在的稀有的5-氧代β-三酮AB5046A和AB5046B可在五个线性步骤中高效合成,总收率分别为36%和28%。合成策略强调了从市售间苯三酚可轻松制备关键中间体3-乙氧基-5-羟基环己-2-烯酮。

更新日期:2018-03-17
down
wechat
bug