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Selective recovery of cadaverine from lysine decarboxylase bioconversion solution using methyl ethyl ketone
Journal of Industrial and Engineering Chemistry ( IF 5.9 ) Pub Date : 2018-08-01 , DOI: 10.1016/j.jiec.2018.03.013
Yun-Gi Hong , Hyun-Joong Kim , Jong-Min Jeon , Yu-Mi Moon , Ju-Won Hong , Jeong-Chan Joo , Bong-Keun Song , Kyung-Mooon Park , Sang-Hyun Lee , Yung-Hun Yang

Abstract Efficient extraction and purification process is still a major bottleneck for economical production of cadaverine. We examined 10 different organic solvents to determine which one might be a suitable solvent for cadaverine extraction. Methyl ethyl ketone (MEK) was a very selective solvent for cadaverine. High pH was critical factor for cadaverine extraction with high purity. Cadaverine extraction efficiency of more than 70.1% with 99% of purity was successfully achieved by applying optimized extraction condition (pH 13.5, 58 °C, 200 rpm incubation for 6 h). Cadaverine extraction using MEK seems quite feasible and promising for the preparation of polyamide monomers for environmental process.

中文翻译:

使用甲基乙基酮从赖氨酸脱羧酶生物转化溶液中选择性回收尸胺

摘要 高效的提取纯化工艺仍然是尸胺经济生产的主要瓶颈。我们检查了 10 种不同的有机溶剂,以确定哪一种可能适合用于尸胺提取。甲乙酮 (MEK) 是一种非常有选择性的尸胺溶剂。高 pH 值是高纯度尸胺提取的关键因素。通过应用优化的提取条件(pH 13.5,58°C,200 rpm 孵育6小时),尸胺提取效率超过70.1%,纯度为99%。使用 MEK 提取尸胺对于制备用于环境过程的聚酰胺单体似乎非常可行和有前景。
更新日期:2018-08-01
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