A series of ultrafiltration (UF) membranes based on polysulfone and mussel-inspired poly(dopamine methacrylamide) (PDMA) were prepared by an in-situ process composed of grafting-through approach and consecutive non-solvent induced phase separation. Nisin, a low molecular weight antimicrobial peptide, was subsequently immobilized on the surface of the UF membrane through the reaction between the NH₂ groups of nisin and catechol groups of PDMA moiety in the membrane. The resulting nisin containing UF membranes showed outstanding fouling resistance and flux recovery ability due to the hydrophilic characteristics of the PDMA moiety, and also exhibited antimicrobial activity against the Staphylococcus aureus (ATCC 6538) due to the nisin moiety.

通过由接枝法和连续的非溶剂诱导的相分离组成的原位制备了一系列基于聚砜和贻贝启发的聚（多巴胺甲基丙烯酰胺）（PDMA）的超滤（UF）膜。随后，通过乳链菌肽的NH ₂基团的NH ₂基与PDMA部分的邻苯二酚基团之间的反应，将乳链菌肽（一种低分子量抗微生物肽）固定在UF膜的表面上。所得的含乳链菌肽的超滤膜由于PDMA部分的亲水特性而表现出出色的抗污性和通量恢复能力，并且还表现出对金黄色葡萄球菌的抗菌活性。 （ATCC 6538）归因于乳链菌肽部分。