Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study.,The Lancet

当前位置： X-MOL 学术 › Lancet › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study.
The Lancet ( IF 98.4 ) Pub Date : 2018-06-01 , DOI: 10.1016/s2213-2600(18)30058-4
Daniel B Hawcutt ₁ , Ben Francis ₂ , Daniel F Carr ₃ , Andrea L Jorgensen ₂ , Peng Yin ₂ , Naomi Wallin ₄ , Natalie O'Hara ₃ , Eunice J Zhang ₃ , Katarzyna M Bloch ₃ , Amitava Ganguli ₃ , Ben Thompson ₃ , Laurence McEvoy ₃ , Matthew Peak ₅ , Andrew A Crawford ₆ , Brian R Walker ₇ , Joanne C Blair ₈ , Jonathan Couriel ₉ , Rosalind L Smyth ₁₀ , Munir Pirmohamed ₃

Affiliation

Department of Women's and Children's Health, University of Liverpool, Liverpool, UK; Wolfson Centre for Personalised Medicine, Medical Research Council (MRC) Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
Department of Biostatistics, University of Liverpool, Liverpool, UK.
Wolfson Centre for Personalised Medicine, Medical Research Council (MRC) Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
Department of Women's and Children's Health, University of Liverpool, Liverpool, UK.
National Institute for Health Research (NIHR) Alder Hey Clinical Research Facility, Alder Hey Children's Hospital, Liverpool, UK.
British Heart Foundation (BHF) Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK; MRC Integrated Epidemiology Unit at the University of Bristol, Bristol, UK.
British Heart Foundation (BHF) Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
Department of Endocrinology, Alder Hey Children's Hospital, Liverpool, UK.
Department of Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, UK.
Great Ormond Street Institute of Child Health, University College London, London, UK.

A serious adverse effect of corticosteroid therapy is adrenal suppression. Our aim was to identify genetic variants affecting susceptibility to corticosteroid-induced adrenal suppression.

中文翻译：