Despite the significance of mitochondrial dynamics in many diseases, drugs that modulate it are lacking. In this issue ofCell Chemical Biology,Miret-Casals et al. (2018)use a phenotypic high-throughput screen to discover a pro-fusion role for the anti-inflammatory drug Leflunomide, paving the way to screen for mitochondrial pro-fusion drug candidates.

中文翻译：

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火焰状线粒体：消炎药来氟米特增强线粒体融合素

尽管线粒体动力学在许多疾病中具有重要意义，但仍缺乏调节线粒体动力学的药物。在本期《细胞化学生物学》中，Miret-Casals等人。（2018）使用表型高通量筛选来发现抗炎药来氟米特的促融合作用，为筛选线粒体促融合药物候选物铺平了道路。