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White-Light-Activated Antibacterial Surfaces Generated by Synergy between Zinc Oxide Nanoparticles and Crystal Violet
ACS Omega ( IF 3.7 ) Pub Date : 2018-03-15 00:00:00 , DOI: 10.1021/acsomega.7b01473
Ekrem Ozkan 1 , Elaine Allan 2 , Ivan P Parkin 1
Affiliation  

The prevalence of hospital-acquired infections (HAIs) caused by multidrug-resistant bacteria is a growing public health concern worldwide. Herein, a facile, easily scalable technique is reported to fabricate white-light-activated bactericidal surfaces by incorporating zinc oxide (ZnO) nanoparticles and crystal violet (CV) dye into poly(dimethylsiloxane). The effect of ZnO concentration on photobactericidal activity of CV is investigated, and we show that there is synergy between ZnO and CV. These materials showed highly significant antibacterial activity when tested against Staphylococcus aureus and Escherichia coli under white light conditions. These surfaces have potential to be used in healthcare environments to decrease the impact of HAIs.

中文翻译:

氧化锌纳米颗粒和结晶紫协同作用产生白光激活抗菌表面

由多重耐药细菌引起的医院获得性感染 (HAI) 的流行是全球日益严重的公共卫生问题。在此,报道了一种简便、易于扩展的技术,通过将氧化锌(ZnO)纳米颗粒和结晶紫(CV)染料掺入聚(二甲基硅氧烷)中来制造白光激活的杀菌表面。研究了 ZnO 浓度对 CV 光杀菌活性的影响,结果表明 ZnO 和 CV 之间存在协同作用。在白光条件下对金黄色葡萄球菌大肠杆菌进行测试时,这些材料显示出高度显着的抗菌活性。这些表面有潜力用于医疗保健环境,以减少医院感染的影响。
更新日期:2018-03-15
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