CAR T cells directed against CSPG4 limit the growth of brain tumors in cultured neurospheres and glioma xenograft mouse models, with no signs of immune escape owing to loss of antigen expression.

中文翻译：

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CSPG4 显示出胶质母细胞瘤 CAR T 疗法的前景

针对CSPG4的CAR T细胞限制了培养的神经球和神经胶质瘤异种移植小鼠模型中脑肿瘤的生长，并且没有由于抗原表达丧失而导致免疫逃逸的迹象。