Dietary impact on esophageal cancer in humans: a review,Food & Function

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Dietary impact on esophageal cancer in humans: a review
Food & Function ( IF 5.1 ) Pub Date : 2018-03-14 00:00:00 , DOI: 10.1039/c7fo01908d
Rachna Khosla Sardana _{1,

2,

3,

4} , Navnidhi Chhikara _{1,

2,

3,

4} , Beenu Tanwar _{4,

5,

6} , Anil Panghal _{1,

2,

3,

4}

Affiliation

Cancer is the abnormal growth of cells that tend to proliferate in an uncontrolled way. About 32.6 million people in the world are affected by different types of cancer; 456 000 have esophageal cancer, which is the eighth most common cancer and the sixth most common cause of cancer-related deaths with a toll of 400 000 in 2012. About 80% of cases were reported from the less developed regions of the world. An incidence ratio of 2.4 : 1 for men and women reveals the gender disparity. Esophageal cancer is mainly of two types, namely, squamous cell carcinoma and adenocarcinoma. Most of the studies show a positive correlation of esophageal cancer with alcohol and tobacco consumption, but a negative correlation with fruit and vegetable intake. The type and amount of cereal, fat, meat and beverages consumed are also under study. Significant statistical synergistic interaction has been registered in studies considering the joint effect of the amount of beverage swallowed and its temperature, especially among heavy consumers. The role of non-nutritional components is gaining increasing attention because of their antioxidant, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties. Socioeconomic status is another factor that cannot be ignored. Nevertheless, the predominant cause appears to be different in different regions, and in spite of the great advancements in the medical field, this still remains an enigma for researchers.

中文翻译：

饮食对人类食道癌的影响：综述

癌症是倾向于以不受控制的方式增殖的细胞的异常生长。世界上约有3260万人患有不同类型的癌症；456 000例食道癌是第八大癌症，也是第六大最常见的癌症相关死亡原因，2012年的死亡人数为40万人。据报告，约80％的病例来自世界欠发达地区。男女的发病比为2.4：1，这表明性别差异。食道癌主要有两种类型，即鳞状细胞癌和腺癌。大多数研究表明，食道癌与烟酒的摄入呈正相关，而与水果和蔬菜的摄入呈负相关。谷物，脂肪，肉类和饮料的消费类型和数量也在研究中。考虑到吞咽饮料量及其温度的共同影响，特别是在重度消费者中，重要的统计协同相互作用已在研究中进行了记录。非营养成分的作用由于其抗氧化，抗炎，抗诱变和抗癌特性而受到越来越多的关注。社会经济地位是另一个不容忽视的因素。然而，在不同地区，其主要起因似乎有所不同，尽管医学领域取得了长足的进步，但对于研究人员而言，这仍然是一个谜。非营养成分的作用由于其抗氧化，抗炎，抗诱变和抗癌特性而受到越来越多的关注。社会经济地位是另一个不容忽视的因素。然而，在不同地区，其主要起因似乎有所不同，尽管医学领域取得了长足的进步，但对于研究人员而言，这仍然是一个谜。非营养成分的作用由于其抗氧化，消炎，抗诱变和抗癌特性而受到越来越多的关注。社会经济地位是另一个不容忽视的因素。然而，在不同地区，其主要起因似乎有所不同，尽管医学领域取得了长足的进步，但对于研究人员而言，这仍然是一个谜。

更新日期：2018-03-14

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