Studies have shown that 5α-reductase inhibitors (5-ARIs) decrease the risk for low-grade prostate cancer (PC), but results are conflicting concerning high-grade PCs. The objective of the present study is to evaluate the association between 5-ARI treatment for lower urinary tract symptoms and the risk for PC.

中文翻译：

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5α-还原酶抑制剂治疗男性前列腺癌的风险-一项基于人群的前瞻性研究。

研究表明5α-还原酶抑制剂（5-ARIs）降低了低级前列腺癌（PC）的风险，但结果与高级别PC矛盾。本研究的目的是评估5-ARI治疗下尿路症状与PC风险之间的关联。