The dietary total antioxidant capacity (TAC) has been a useful tool in epidemiological studies. To assess whether the TAC is associated with chronic diseases in middle-aged and older adults carried out a systematic review of articles indexed in MEDLINE and Science Direct. Of the 104 articles found, nine were included to meet the inclusion criteria. There was variation among the items on the sample size, sample origin, use of statistical tests, analysis of different outcomes and the use of assays to evaluate the TAC, which brought limitations to the comparability of results on the association of TAC with the outcomes of interest. However, in six studies we found an inverse association between TAC and the risk of chronic diseases, showing that this method has great potential for clinical applications and public health.

中文翻译：

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饮食中总抗氧化剂作为中老年人健康结果的工具：系统评价

饮食中的总抗氧化能力（TAC）已成为流行病学研究中的有用工具。为了评估TAC是否与中老年人的慢性疾病有关，对MEDLINE和Science Direct收录的文章进行了系统的综述。在发现的104篇文章中，有9篇符合入选标准。样本大小，样本来源，使用统计测试，分析不同结果以及使用分析方法评估TAC的项目之间存在差异，这限制了TAC与TAC结果之间关联性的结果可比性兴趣。但是，在六项研究中，我们发现TAC与慢性病风险之间存在负相关关系，表明该方法在临床应用和公共卫生方面具有巨大潜力。