Recruitment of thermogenic adipocytes within white fat depots represents a promising strategy to increase energy expenditure. Negative energy balance has been reported to promote adipose tissue browning in rodents. In a recent issue of Cell Reports, Barquissau et al. show that caloric restriction-associated weight loss does not induce browning of subcutaneous abdominal white fat in obese humans.

中文翻译：

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人类的减肥和脂肪组织褐变：是鸡还是蛋？

在白色脂肪库中招募产热脂肪细胞代表了增加能量消耗的有希望的策略。据报道，负能量平衡会促进啮齿动物的脂肪组织褐变。在最近一期的 Cell Reports 中，Barquissau 等人。表明热量限制相关的体重减轻不会导致肥胖人的皮下腹部白色脂肪变褐。