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Lean ApoM −/− Mice with Hyperactive Brown Adipose Tissue
Trends in Endocrinology & Metabolism ( IF 10.9 ) Pub Date : 2018-05-01 , DOI: 10.1016/j.tem.2018.02.011
Björn Dahlbäck

In Cell Reports, Christoffersen et al. [1] demonstrate that sphingosine 1-phosphate (S1P) bound to apolipoprotein M (apoM) regulates the activity and mass of brown adipose tissue (BAT). They found mice lacking apoM to have hyperactive BAT with high triglyceride (TG) utilization, resulting in low white adipose tissue (WAT) mass and low body weight.

中文翻译:

具有过度活跃的棕色脂肪组织的精益 ApoM -/- 小鼠

在细胞报告中,克里斯托弗森等人。[1] 证明与载脂蛋白 M (apoM) 结合的 1-磷酸鞘氨醇 (S1P) 调节棕色脂肪组织 (BAT) 的活性和质量。他们发现缺乏 apoM 的小鼠的 BAT 过度活跃,甘油三酯 (TG) 利用率高,导致白色脂肪组织 (WAT) 质量低和体重低。
更新日期:2018-05-01
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