The Oral Bioavailability of Trans‐Resveratrol from a Grapevine‐Shoot Extract in Healthy Humans is Significantly Increased by Micellar Solubilization,Molecular Nutrition & Food Research

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The Oral Bioavailability of Trans‐Resveratrol from a Grapevine‐Shoot Extract in Healthy Humans is Significantly Increased by Micellar Solubilization
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2018-04-30 , DOI: 10.1002/mnfr.201701057
Laura A. Calvo-Castro _{1,

2} , Christina Schiborr ₁ , Franziska David ₁ , Heidi Ehrt ₁ , Jenny Voggel ₁ , Nadine Sus ₁ , Dariush Behnam ₃ , Anja Bosy-Westphal ₄ , Jan Frank ₁

Affiliation

Grapevine‐shoot extract Vineatrol30 contains abundant resveratrol monomers and oligomers with health‐promoting potential. However, the oral bioavailability of these compounds in humans is low (˂1–2%). The aim of this study was to improve the oral bioavailability of resveratrol from vineatrol by micellar solubilization.

中文翻译：

胶束增溶作用显着提高了健康人葡萄藤提取物中反式白藜芦醇的口服生物利用度

葡萄枝提取物Vineatrol30含有丰富的白藜芦醇单体和低聚物，具有促进健康的潜力。但是，这些化合物在人体中的口服生物利用度较低（˂1-2％）。这项研究的目的是通过胶束增溶作用来提高白藜芦醇中白藜芦醇的口服生物利用度。

更新日期：2018-04-30

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