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Glucose Metabolism in Cancer: The Saga of Pyruvate Kinase Continues.
Cancer Cell ( IF 50.3 ) Pub Date : 2018-03-12 , DOI: 10.1016/j.ccell.2018.02.008
Annamarie E. Allen , Jason W. Locasale

Altered glucose metabolism is common in cancer. In this issue of Cancer Cell, Morita et al. report new mouse models that express specific isoforms of pyruvate kinase to study glycolysis in tumors. They report several unanticipated findings that challenge current ideas in cancer metabolism.

中文翻译:

癌症中的葡萄糖代谢:丙酮酸激酶的传奇继续。

葡萄糖代谢改变在癌症中很常见。在此期的《癌细胞》中,森田(Morita)等人。报道了表达丙酮酸激酶特定同工型的新型小鼠模型,以研究肿瘤中的糖酵解。他们报告了一些未曾预料到的发现,这些发现挑战了当前癌症代谢的观念。
更新日期:2018-03-13
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