Abstract Biofouling in membrane bioreactors (MBRs), which is defined as the unwanted accumulation of microorganisms on the membrane surface, has been intensively studied for more than two decades. However, it remains a critical limiting factor to the more widespread use of MBR for wastewater treatment. The concept of quorum sensing (QS) / quorum quenching (QQ) was proposed as an anti-fouling strategy for MBRs in 2002 and the first paper on that issue was published in 2009. Since then, many studies have demonstrated and proved the potential of QQ for biofouling control in MBR through various means. The evolution of QQ-MBR has had a run of eight years in terms of QQ-microorganisms, QQ-media, and the size of the QQ-MBRs tested. This review provides an overview on the QS/QQ studies related to the elucidation and control of biofouling in MBRs, including the identification of QS signals, the isolation of QS signal producing or degrading microorganisms, and various engineering approaches to apply enzymatic or bacterial QQ in the form of QQ-media to mitigate membrane biofouling. The challenges confronting these applications and future directions of QQ-based biofouling control strategies for MBR are discussed.

中文翻译：

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用于废水处理的 MBR 生物污垢控制的定额淬火技术的起源和演变

摘要 膜生物反应器 (MBR) 中的生物污染被定义为微生物在膜表面上的有害积累，已被深入研究了二十多年。然而，它仍然是更广泛地使用 MBR 进行废水处理的关键限制因素。群体感应 (QS) / 群体淬灭 (QQ) 的概念于 2002 年被提出作为 MBR 的防污策略，并于 2009 年发表了关于该问题的第一篇论文。 从那时起，许多研究已经证明并证明了QQ 通过多种方式控制 MBR 中的生物污垢。QQ-MBR 在 QQ 微生物、QQ 媒体和所测试的 QQ-MBR 的大小方面的发展已经运行了八年。本综述概述了与 MBR 中生物污垢的阐明和控制相关的 QS/QQ 研究，包括鉴定 QS 信号、分离产生或降解 QS 信号的微生物，以及以 QQ 介质形式应用酶或细菌 QQ 以减轻膜生物污染的各种工程方法。讨论了这些应用面临的挑战以及基于 QQ 的 MBR 生物污垢控制策略的未来方向。