Prion-like proteins overlap with intrinsically disordered and low-complexity sequence families. These proteins are widespread, especially among mRNA-binding proteins. A salient feature of these proteins is the ability to form protein assemblies with distinct biophysical and functional properties. While prion-like proteins are involved in myriad of cellular processes, we propose potential roles for protein assemblies in regulated protein synthesis. Since proteins are the ultimate functional output of gene expression, when, where, and how much of a particular protein is made dictates the functional state of a cell. Recent finding suggests that the prion-like proteins offer unique advantages in translation regulation and also raises questions regarding formation and regulation of protein assemblies.

on病毒样蛋白与内在无序和低复杂度的序列家族重叠。这些蛋白质是普遍存在的，尤其是在mRNA结合蛋白质中。这些蛋白质的显着特征是能够形成具有独特生物物理和功能特性的蛋白质装配体。尽管病毒样蛋白参与了无数的细胞过程，但我们提出了蛋白质组装在调控蛋白合成中的潜在作用。由于蛋白质是基因表达的最终功能输出，因此何时，何地以及制造多少特定蛋白质决定了细胞的功能状态。最近的发现表明the病毒样蛋白在翻译调控中提供了独特的优势，并且也提出了有关蛋白质装配体的形成和调控的问题。