In an article published in the Annals of the Rheumatic Diseases , Schieir et al 1 reported a trend of increased cardiovascular risk in patients with ankylosing spondylitis (AS). In this letter, we wish to add data to support the conclusions of that article. We performed an updated meta-analysis to investigate the risks of myocardial infarction (MI) and stroke in patients with AS and controls. We searched PubMed to find reports of interest, published up to February 2018. We included all observational or case/control studies that reported rates of MI or stroke. We calculated the incidences of MI and stroke in a meta-analysis of proportions (inverse variance method) and expressed them in terms of …

中文翻译：

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强直性脊柱炎的心血管事件：2018 年荟萃分析

在《风湿病年鉴》上发表的一篇文章中，Schieir 等人 1 报告了强直性脊柱炎 (AS) 患者心血管风险增加的趋势。在这封信中，我们希望添加数据来支持该文章的结论。我们进行了一项更新的荟萃分析，以调查 AS 患者和对照组发生心肌梗塞 (MI) 和中风的风险。我们搜索了 PubMed 以查找截至 2018 年 2 月发表的感兴趣的报告。我们纳入了所有报告 MI 或中风发生率的观察性或病例/对照研究。我们在比例的荟萃分析（逆方差法）中计算了 MI 和中风的发生率，并用……