Miniaturized Reverse Electrodialysis-Powered Biosensor Using Electrochemiluminescence on Bipolar Electrode,Analytical Chemistry

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Miniaturized Reverse Electrodialysis-Powered Biosensor Using Electrochemiluminescence on Bipolar Electrode
Analytical Chemistry ( IF 6.7 ) Pub Date : 2018-03-09 00:00:00 , DOI: 10.1021/acs.analchem.7b05425
Seol Baek ₁ , Seung-Ryong Kwon ₁ , Song Yi Yeon ₁ , Sun-Heui Yoon ₁ , Chung Mu Kang ₂ , Seok Hee Han ₁ , Dahye Lee ₁ , Taek Dong Chung _{1,

2}

Affiliation

We suggest an electrochemiluminescence (ECL)-sensing platform driven by ecofriendly, disposable, and miniaturized reverse electrodialysis (RED) patches as an electric power source. The flexible RED patches composed of ion-exchange membranes (IEMs) can produce voltage required for ECL sensing by simply choosing the appropriate number of IEMs and the ratio of salt concentrations. We integrate the RED patch with a bipolar electrode on the microfluidic chip to demonstrate the proof-of-concept, i.e., glucose detection in the range of 0.5–10 mM by observing ECL emissions with naked eyes. The miniaturized RED-powered biosensing system is widely applicable for electrochemical-sensing platforms. This is expected to be a solution for practical availability of battery-free electrochemical sensors for disease diagnosis in developing countries.

更新日期：2018-03-09

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