Dynamic alterations of hepatocellular function by on-demand elasticity and roughness modulation†,Biomaterials Science

当前位置： X-MOL 学术 › Biomater. Sci. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Dynamic alterations of hepatocellular function by on-demand elasticity and roughness modulation†
Biomaterials Science ( IF 5.8 ) Pub Date : 2018-03-09 00:00:00 , DOI: 10.1039/c8bm00047f
K. Uto _{1,

2,

3,

4,

5} , T. Aoyagi _{4,

6,

7,

8,

9} , C. A. DeForest _{10,

11,

12,

13} , M. Ebara _{2,

3,

4,

14}

Affiliation

Temperature-responsive cell culture substrates reported here can be dynamically programmed to induce bulk softening and surface roughness changes in the presence of living cells. Alterations in hepatocellular function following temporally controlled substrate softening depend on the extent of stiff mechanical priming prior to user-induced material transition.

中文翻译：