&NA; The electronic nose (e‐nose) is a promising technology as a useful addition to the currently available modalities to achieve lung cancer diagnosis. The e‐nose can assess the volatile organic compounds detected in the breath and derived from the cellular metabolism. Volatile organic compounds can be analyzed to identify the individual chemical elements as well as their pattern of expression to reproduce a sensorial combination similar to a fingerprint (breathprint). The e‐nose can be used alone, mimicking the combinatorial selectivity of the human olfactory system, or as part of a multisensorial platform. This review analyzes the progress made by investigators interested in this technology as well as the perspectives for its future utilization.

中文翻译：

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肺癌的呼吸印记与早期诊断

&NA; 电子鼻（e-nose）是一项很有前途的技术，可以作为目前可用的肺癌诊断方法的有用补充。电子鼻可以评估在呼吸中检测到的来自细胞代谢的挥发性有机化合物。可以分析挥发性有机化合物以识别单个化学元素及其表达模式，以重现类似于指纹（呼吸印）的感官组合。电子鼻可以单独使用，模仿人类嗅觉系统的组合选择性，或作为多感官平台的一部分。本综述分析了对该技术感兴趣的研究人员取得的进展，以及对其未来利用的前景。