Enzymes working in reverse

Enzymes working in reverse, Published online: 08 March 2018; doi:10.1038/s41929-018-0041-5

Lyases are enzymes that catalyse the breaking of chemical bonds. Now, reversing this reaction towards carbon–nitrogen bond formation allows for the synthesis of various chiral aminocarboxylic acids such as the potential antibiotic co-drug aspergillomarasmine A.

中文翻译：

---

反向酶

反向酶

反向作用的酶，在线发布：2018年3月8日; doi：10.1038 / s41929-018-0041-5

裂解酶是催化化学键断裂的酶。现在，将该反应逆转为形成碳氮键的过程，可以合成各种手性氨基羧酸，例如潜在的抗生素联用药物曲霉氨基arasmineA。