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Structure and biosynthesis of mayamycin B, a new polyketide with antibacterial activity from Streptomyces sp. 120454.
The Journal of Antibiotics ( IF 2.1 ) Pub Date : 2018-Jun-01 , DOI: 10.1038/s41429-018-0039-x
Sheng Tao Bo , Zi Fei Xu , Li Yang , Ping Cheng , Ren Xiang Tan , Rui Hua Jiao , Hui Ming Ge

Mayamycin B, a new antibacterial type II polyketide, together with its known congener mayamycin A, were isolated from Streptomyces sp. 120454. The structure of new compound was elucidated by extensive spectroscopic analysis and comparison with literature data. Sequencing and bioinformatics analysis revealed the biosynthetic gene cluster for mayamycins A and B.

中文翻译:

玛雅霉素B的结构和生物合成,一种来自链霉菌属的具有抗菌活性的新型聚酮化合物。120454。

从链霉菌(Streptomyces sp)中分离到一种新的抗菌II型聚酮霉素霉素B及其已知的同源霉素霉素A。120454.通过广泛的光谱分析和与文献数据的比较,阐明了新化合物的结构。测序和生物信息学分析揭示了玛雅霉素A和B的生物合成基因簇。
更新日期:2018-03-07
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