当前位置: X-MOL 学术Trends Biochem. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The Cytokinin-Activating LOG-Family Proteins Are Not Lysine Decarboxylases
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2018-03-07 , DOI: 10.1016/j.tibs.2018.01.002
Muhammad Naseem , Elena Bencurova , Thomas Dandekar

A conserved PGGxGTxxE motif misleads the cytokinin (CK) converting LONELY GUY enzymes to be wrongly annotated as lysine decarboxylases (LDCs). However, so far PGGxGTxxE motif-containing LDCs do not show any LDC activity. Instead, they show phosphoribohydrolase activity by converting inactive CK nucleotides into active free-base forms to invoke CK responses.



中文翻译:

激活细胞分裂素的LOG家族蛋白不是赖氨酸脱羧酶

保守的PGGxGTxxE基序会误导细胞分裂素(CK),从而将孤独的GUY酶错误地标注为赖氨酸脱羧酶(LDC)。但是,到目前为止,包含PGGxGTxxE基序的LDC均未显示任何LDC活性。相反,它们通过将非活性的CK核苷酸转化为活性的游离碱形式来显示CK响应,从而显示出磷酸氢水解酶的活性。

更新日期:2018-03-07
down
wechat
bug