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Hybrid Materials: Flexible Modulation of CO‐Release Using Various Nuclearity of Metal Carbonyl Clusters on Graphene Oxide for Stroke Remediation (Adv. Healthcare Mater. 5/2018)
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2018-03-07 , DOI: 10.1002/adhm.201870022
Mein Jin Tan,Han-Chi Pan,Hui Ru Tan,Jian Wei Chai,Qi Feng Lim,Ten It Wong,Xiaodong Zhou,Zi-Yao Hong,Lun-De Liao,Kien Voon Kong

A facile CO‐release material for in‐situ vasodilation as a treatment for stroke‐related vascular diseases is developed by K.V. Kong, L.D. Liao and co‐workers in article number 1701113. Utilizing the size dependent adsorption properties of ruthenium carbonyl clusters (Ru‐CO) onto graphene oxide (GO), the rate and amount of formation of the CO release‐active RuII(CO)2 species can be modulated by a simple mixing procedure. Further modulation of thermal and CO release properties can be achieved via a hybridization of medium‐ and high‐ nuclearity of Ru‐CO clusters that can provide photo‐thermal response for in‐situ CO release in a cortical photo‐thrombotic ischemia rat model.
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中文翻译:

混合材料:使用氧化石墨烯上的金属羰基簇的各种核原子来灵活地调节CO释放,以修复中风(Adv。Healthcare Mater.5 / 2018)

KV Kong,LD Liao及其同事在文章编号1701113中开发了一种用于原位血管舒张的轻度CO释放材料,用于治疗中风相关的血管疾病。利用钌羰基簇(Ru-将CO)释放到氧化石墨烯(GO)上,可以通过简单的混合程序调节释放CO的活性Ru II(CO)2物种的形成速率和数量。通过Ru-CO团簇的中核和高核能的混合,可以进一步调节热和CO的释放特性,这可以为皮层光血栓性缺血大鼠模型中的原位CO释放提供光热响应。
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更新日期:2018-03-07
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