Caenorhabditis elegans (C. elegans) is a free-living nematode that has been extensively utilized as an animal model for research involving aging and neurodegenerative diseases, like Alzheimer's and Parkinson's, etc. Compared with traditional animal models, this small nematode possesses many benefits, such as small body size, short lifespan, completely sequenced genome, and more than 65% of the genes associated with human disease. All these characteristics make this organism an ideal living system for obesity and aging studies. This review gives a brief introduction of C. elegans as an animal model, highlights some advantages of research using this model and describes methods to evaluate the effect of treatments on obesity and aging of this organism.

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肥胖和衰老研究的生活模型：秀丽隐杆线虫

秀丽隐杆线虫是一种自由生存的线虫，已广泛用作涉及衰老和神经退行性疾病（例如阿尔茨海默氏病和帕金森氏病等）的动物模型。与传统动物模型相比，这种小型线虫具有许多优势，例如体积小，寿命短，基因组已完全测序，以及超过65％的与人类疾病相关的基因。所有这些特征使该生物体成为肥胖和衰老研究的理想生命系统。这篇综述简要介绍了秀丽隐杆线虫作为一种动物模型，强调了使用该模型进行研究的一些优势，并描述了评估治疗方法对该生物的肥胖和衰老的影响的方法。