Hydrophobic effect: The incorporation into peptides of amino acids containing CF₃ or SCF₃ groups constitutes a powerful strategy for dramatically increasing and tuning the peptides’ local hydrophobicity. Hydrophobicity indexes (ϕ₀) derived from RP‐HPLC provide accurate measurements of these outstanding hydrophobicity increases.

中文翻译：

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探索由于引入三氟甲基化氨基酸而引起的肽序列中局部疏水性的增加

疏水作用：将含有CF ₃或SCF ₃基团的氨基酸掺入肽中可构成一种强有力的策略，可显着提高和调节肽的局部疏水性。源自RP‐HPLC的疏水性指数（ϕ ₀）可准确测量这些显着的疏水性增加。