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Advances in the approach to the patient with food allergy
Journal of Allergy and Clinical Immunology ( IF 11.4 ) Pub Date : 2018-03-08 , DOI: 10.1016/j.jaci.2017.12.1008
Amy M. Scurlock , Stacie M. Jones

Advances in food allergy diagnosis, management, prevention, and therapeutic interventions have been significant over the past 2 decades. Evidence-based national and international guidelines have streamlined food allergy diagnosis and management, whereas paradigm-shifting work in primary prevention of peanut allergy has resulted in significant modifications in the approach to early food introduction in infants and toddlers. Innovative investigation of food allergy epidemiology, systems biology, effect, and management has provided important insights. Although active therapeutic approaches to food allergy remain experimental, progress toward licensed therapies has been substantial. Mechanistic understanding of the immunologic processes underlying food allergy and immunotherapy will inform the future design of therapeutic approaches targeting the food-induced allergic response. Global strategies to mitigate the substantial medical, economic, and psychosocial burden of food allergy in affected subjects and families will require engagement of stakeholders across multiple sectors in research, health care, public health, government, educational institutions, and industry. However, the relationship between the well-informed allergy care provider and the patient and family remains fundamental for optimizing the care of the patient with food allergy.



中文翻译:

食物过敏患者的治疗方法的进展

在过去的20年中,食物过敏的诊断,管理,预防和治疗干预措施取得了重大进展。以证据为基础的国家和国际准则简化了食物过敏的诊断和管理,而对花生过敏的一级预防中的范式转换工作对婴幼儿早期引入食物的方法进行了重大修改。对食物过敏流行病学,系统生物学,作用和管理的创新研究提供了重要的见识。尽管对食物过敏的有效治疗方法仍处于试验阶段,但在许可疗法方面已取得了实质性进展。对食物过敏和免疫疗法基础的免疫学过程的机械理解将为针对食物诱发的过敏反应的治疗方法的未来设计提供指导。减轻受影响对象和家庭中食物过敏的重大医学,经济和社会心理负担的全球战略将要求研究,卫生保健,公共卫生,政府,教育机构和行业的多个部门的利益相关者参与。然而,消息灵通的过敏护理提供者与患者和家人之间的关系对于优化食物过敏患者的护理仍然至关重要。以及受影响对象和家庭的食物过敏的社会心理负担,将需要利益相关者参与研究,医疗保健,公共卫生,政府,教育机构和行业的多个部门。然而,消息灵通的过敏护理提供者与患者和家人之间的关系对于优化食物过敏患者的护理仍然至关重要。以及受影响对象和家庭的食物过敏的社会心理负担,将需要利益相关者参与研究,医疗保健,公共卫生,政府,教育机构和行业的多个部门。然而,消息灵通的过敏护理提供者与患者和家人之间的关系仍然是优化食物过敏患者护理的基础。

更新日期:2018-03-08
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