The cell cycle and the circadian clock operate as biological oscillators whose timed functions are tightly regulated. Accumulating evidence illustrates the presence of molecular links between these two oscillators. This mutual interplay utilizes various coupling mechanisms, such as the use of common regulators. The connection between these two cyclic systems has unique interest in the context of aberrant cell proliferation since both of these oscillators are frequently misregulated in cancer cells. Further studies will provide deeper understanding of the detailed molecular connections between the cell cycle and the circadian clock and may also serve as a basis for the design of innovative therapeutic strategies.

细胞周期和生物钟作为生物振荡器运行，其定时功能受到严格调节。越来越多的证据表明这两个振荡器之间存在分子链接。这种相互影响利用各种耦合机制，例如使用通用调节器。在细胞异常增殖的情况下，这两个循环系统之间的联系具有独特的意义，因为这两个振荡器在癌细胞中经常被错误地调节。进一步的研究将提供对细胞周期与昼夜节律时钟之间的详细分子联系的更深入理解，并且也可作为设计创新治疗策略的基础。