Electroconvulsive therapy (ECT) remains a treatment that raises controversy despite its endorsement for specific indications by clinical guidelines such as those from the UK National Institute for Health and Care Excellence.¹ Central to the controversy is disagreement over the balance between the potential benefits and harms of ECT, especially in a patient group whose severity of illness arguably makes them particularly vulnerable. In The Lancet Psychiatry, Merete Osler and colleagues² report the findings from their cohort study of patients in Denmark with a first hospital contact for an affective disorder from 2005 to end of 2015, comparing the incidence of dementia in those who had received ECT with those who had not.

中文翻译：

---

抽搐治疗会损害大脑吗？

电痉挛疗法（ECT）仍然引起争议，尽管它已得到临床指南（例如英国国立健康与护理卓越研究所的认可）对特定适应症的认可。¹争议的中心是在ECT的潜在利与弊之间的平衡上存在分歧，尤其是在疾病严重程度可能使其特别脆弱的患者群体中。在《柳叶刀精神病学》中，Merete Osler及其同事²报告了他们对2005年至2015年底首次因情感障碍住院的丹麦患者进行队列研究的结果，将接受ECT的痴呆症患者与接受ECT的痴呆症患者的发生率进行了比较谁没有。