Cymbopogon species are used as traditional remedies in Burkina Faso for treating several diseases. We aimed to study the effects of their essential oils on cancer cell lines. For that purpose, Cymbopogon citratus (DC.) Stapf. and Cymbopogon giganteus Chiov. were studied for their essential oils after various chemical extractions. Antioxidant, potential anti-inflammatory action (inhibition of lipoxygenase) and cytotoxic activities were also tested on various prostate cancer and glioblastoma cell lines. Thirty-three compounds were identified in the essential oil of C. giganteus: Limonene (19.33%), Mentha-1(7),8-dien-2-ol cis (17.34%), Mentha-1(7),8-dien-2-ol trans (13.95%), trans-Mentha-2,8-diene-para-ol 1 (13.91%) and Mentha-2,8-diene-1-ol, cis-para (8.10%) were the most abundant. C. citratus essential oil contained 15 compounds and the major ones were geranial/citral A (48.18%) and neral/citral B (34.37%). Essential oil of C. citratus showed the highest ability to scavenge DPPH⁺ radicals (approximately 68% at 8 mg/mL) while C. giganteus exhibited the highest capability to reduce ABTS⁺ (0.59μmolET/g). The essential oil of C. citratus was the most effective on prostate cell lines LNCaP (IC₅₀ = 6.36 μg/ml) and PC-3 (IC₅₀ = 32.1 μg/ml), and on glioblastoma cell lines (SF-767 (IC₅₀ = 45.13 μg/ml) and SF-763 (IC₅₀ = 172.05 μg/ml). Interestingly, the activity of essential oil of C. citratus was statistically equal to that of its major component, citral. Combination of both oils showed antagonist, additive, indifferent and synergistic effects on LNCaP, PC-3, SF-767 and SF-763 cell lines, respectively. In conclusion, plants from the traditional medicine in Burkina Faso could be of interest for identifying new compounds, such as citral, for the treatment of prostate cancer and glioblastoma.

ym柏属物种被用作布基纳法索的传统疗法，用于治疗多种疾病。我们旨在研究其精油对癌细胞系的影响。为此，请使用柠檬柏（Cymbopogon citratus）（DC。）Stapf。和Cymbopogon giganteus Chiov。经过各种化学提取后，对其香精油进行了研究。还对各种前列腺癌和胶质母细胞瘤细胞系进行了抗氧化剂，潜在的抗炎作用（脂氧化酶的抑制）和细胞毒性活性的测试。在巨型梭状芽胞杆菌的精油中鉴定出33种化合物：柠檬烯（19.33％），Mentha-1（7），8-dien-2-ol顺式（17.34％），Mentha-1（7），8-dien-2-ol反式（13.95％），反门塔-2,8-二烯-对-醇1（13.91％）和Mentha-2,8-二烯-1-醇，顺-对（8.10％）含量最高。C. citratus精油含有15种化合物和主要的是香叶/柠檬醛A（48.18％）和橙花醛/柠檬醛B（34.37％）。精油C. citratus的显示出最高的能力清除DPPH ⁺自由基（在约68％8毫克/毫升），而C.巨表现出减少ABTS最高能力⁺（0.59μmolET/克）。柠檬衣梭菌精油对前列腺细胞系LNCaP（IC ₅₀  = 6.36μg/ ml）和PC-3（IC₅₀  = 32.1微克/毫升），并在成胶质细胞瘤细胞系（SF-767（IC ₅₀  = 45.13微克/毫升）和SF-763（IC ₅₀  = 172.05微克/毫升）。有趣的是，精油活性C. citratus统计学等于其主要成分，两种油的柠檬醛。组合显示出拮抗剂，添加剂，对LNCaP淡漠和协同效应，PC-3，SF-767和SF-763细胞系，分别的。总之，从植物中布基纳法索的传统医学可能对于识别新化合物（例如柠檬醛）以治疗前列腺癌和胶质母细胞瘤感兴趣。