Abstract Compilation of novel surfactant–protein mixtures has always been an intriguing and fascinating domain owing to their implications in industrial and cosmetic realms. In this regard, herein; we have synthesized a new cleavable gemini surfactant and investigated its influence on the structural characteristics of lysozyme via state-of-art techniques. Results have demonstrated the complex formation, unfolding and stabilization of lysozyme upon gemini surfactant combination. Docking/DFT has shown that gemini binds in the vicinity of hydrophobic residues (Trp/Tyr) and interacts via both electrostatic and hydrophobic contributions. This study may be significant to devise novel surfactant–protein mixtures for their end use at industrial stratum.

中文翻译：

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具有溶菌酶的新型双子表面活性剂的合成和生物物理分析：工业视角

摘要 新型表面活性剂-蛋白质混合物的合成一直是一个有趣且引人入胜的领域，因为它们在工业和化妆品领域具有重要意义。在这方面，在此；我们合成了一种新的可裂解双子表面活性剂，并通过最先进的技术研究了其对溶菌酶结构特征的影响。结果证明了双子表面活性剂组合后溶菌酶的复杂形成、解折叠和稳定化。对接/DFT 表明双子座在疏水残基 (Trp/Tyr) 附近结合，并通过静电和疏水作用相互作用。这项研究对于设计新型表面活性剂-蛋白质混合物以用于工业阶层的最终用途可能具有重要意义。