NiMn layered hydroxide compounds have been found to be efficient catalysts for the oxidative dehydrogenation of N-heterocycles by molecular oxygen under mild conditions. Various tetrahydroquinoline derivatives and some other N-heterocycles have been found to be tolerated by the catalytic system. A synergistic effect between Ni and Mn has been observed in the reaction. A kinetic study concluded that the dehydrogenation of 1,2,3,4-tetrahydroquinoline is a first-order reaction, and an apparent activation energy of 113 kJ/mol has been obtained. A probable reaction mechanism comprising an imine intermediate has been proposed according to the obtained results and XPS analysis. The key catalytic site for the dehydrogenation is thought to be Mn³⁺, which could be stabilized by Ni²⁺ in the hydrotalcite structure.

已发现NiMn层状氢氧化物是在温和条件下通过分子氧对N-杂环进行氧化脱氢的有效催化剂。已经发现各种四氢喹啉衍生物和一些其他N-杂环可被催化体系所耐受。在反应中已经观察到Ni和Mn之间的协同作用。动力学研究得出1,2,3,4-四氢喹啉的脱氢反应是一级反应，表观活化能为113 kJ / mol。根据获得的结果和XPS分析，提出了一种可能的包含亚胺中间体的反应机理。认为脱氢的关键催化位点是Mn ³⁺，可以通过Ni ²⁺使其稳定。 在水滑石结构中。