Among all patients referred for stress myocardial perfusion imaging (MPI), a substantial proportion in contemporary practice cannot exercise. Another group of patients are those who are thought to be able to achieve an adequate workload with treadmill (or bicycle) exercise but do not achieve at least 85% of maximum predicted heart rate without developing symptoms. There has been substantial interest and literature on the adjunctive use of vasodilator stress during the same visit to generate best-quality results for patients who do not exercise adequately. Current American Society of Nuclear Cardiology Guidelines recommend the possible use of vasodilator stress agents to supplement exercise in those patients who do not achieve target heart rate. However, optimal timing of administration is not clear. Herein, we summarize literature to date on the combination of vasodilator and exercise stress testing in light of the recently published Exercise to Regadenoson in Recovery Trial (EXERRT).

在所有接受过压力心肌灌注显像（MPI）的患者中，当代实践中有很大一部分无法锻炼。另一组患者是那些认为可以通过跑步机（或自行车）锻炼达到足够的工作量，但没有达到最大预测心率的至少85％而不会出现症状的患者。对于在同一次就诊期间辅助使用血管舒张压来为运动量不足的患者产生最佳质量的结果，已有大量的兴趣和文献报道。当前的美国核心脏病学会指南建议，对于那些未达到目标心率的患者，可以使用血管舒张剂来补充运动。但是，最佳给药时机尚不清楚。在此处，