Background

Patients with hidradenitis suppurativa (HS) experience chronic pain and have significant physical, emotional, and psychological disease impact. These patients may be at risk for substance abuse.

Objective

To evaluate substance use disorder (SUD) among patients with HS in the United States.

Methods

This cross-sectional analysis of adult HS patients (n = 32,625) identified using electronic health records data was pulled from a population-based sample of >50 million patients.

Results

The prevalence of SUD among patients with HS was 4.0% (1315/32,625) compared to 2.0% (195,260/9,581,640) for patients without HS (P < .001). The most common forms of substance misuse among HS patients were alcohol (630/1315, 47.9% of SUD cases), followed by opioids (430/1315, 32.7% of SUD cases) and cannabis (430/1315, 29.7% of SUD cases). Patients with HS had 1.50 (95% confidence interval 1.42-1.59) times the adjusted odds of SUD compared to patients without HS. Patients with HS had significantly greater odds of SUD across demographic subgroups. The association between HS and SUD was generally stronger for patients 45 to 64 years of age, nonwhites, privately insured, and those without depressive or anxiety disorder.

Limitations

SUD may not be accurately diagnosed.

Conclusion

Patients with HS have higher odds of SUD and may benefit from periodic screening for substance abuse.

中文翻译：

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阿片类药物，化脓性汗腺炎患者中的阿片类药物，酒精和大麻滥用：美国一项基于人群的分析

背景

化脓性汗腺炎（HS）患者会经历慢性疼痛，并对身体，情感和心理疾病产生重大影响。这些患者可能有滥用药物的风险。

客观的

评估美国HS患者中的物质使用障碍（SUD）。

方法

使用电子健康记录数据确定的成年HS患者（n = 32,625）的这一横断面分析是从基于人口的超过5,000万患者的样本中得出的。

结果

HS患者中SUD的患病率为4.0％（1315 / 32,625），而HS患者中SUD的患病率为2.0％（195,260 / 9,581,640）（P  <.001）。HS患者中最常见的药物滥用形式是酒精（630/1315，占SUD病例的47.9％），其次是阿片类药物（430/1315，占SUD病例的32.7％）和大麻（430/1315，占SUD病例的29.7％）。 ）。与没有HS的患者相比，HS的患者的SUD调整后几率是1.50（95％置信区间1.42-1.59）倍。HS的患者在各个人口子组中发生SUD的几率明显更高。对于45至64岁，非白人，有私人保险以及无抑郁或焦虑症的患者，HS和SUD之间的关联通常更强。

局限性

SUD可能无法准确诊断。

结论

患有HS的患者发生SUD的几率更高，并且可能会受益于定期筛查药物滥用情况。