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An Endogenous Vaccine Based on Fluorophores and Multivalent Immunoadjuvants Regulates Tumor Micro-Environment for Synergistic Photothermal and Immunotherapy
Theranostics ( IF 12.4 ) Pub Date : 2018-01-01 , DOI: 10.7150/thno.19826
Ling Li , Suleixin Yang , Linjiang Song , Yan Zeng , Tao He , Ning Wang , Chuan Yu , Tao Yin , Li Liu , Xiawei Wei , Qinjie Wu , Yuquan Wei , Li Yang , Changyang Gong

Recently, near-infrared (NIR) light-based photothermal therapy (PTT) has been widely applied in cancer treatment. However, in most cases, the tissue penetration depth of NIR light is not sufficient and thus photothermal therapy is unable to completely eradicate deep, seated tumors inevitably leading to recurrence of the tumor. Due to this significant limitation of NIR, improved therapeutic strategies are urgently needed.

中文翻译:

基于荧光团和多价免疫佐剂的内源性疫苗调节肿瘤微环境的协同光热和免疫治疗。

近来,基于近红外(NIR)光的光热疗法(PTT)已广泛应用于癌症治疗。然而,在大多数情况下,近红外光的组织穿透深度不足,因此光热疗法无法完全根除深处的肿瘤,不可避免地导致肿瘤复发。由于NIR的显着局限性,迫切需要改进的治疗策略。
更新日期:2018-03-01
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