Supramolecular self-assembly based on organic/inorganic hybrids provides a powerful strategy to construct novel nanostructured materials. Polyoxometalates acting as a type of remarkable inorganic building units have widely applied in the field of supramolecular assembly toward biorelevant materials and has attracted great interests in the fields of colloid and interface chemistry, nanomaterials and medical science. The surface of polyanionic clusters can be modified by cationic organic surfactants, biomolecules and polymers via electrostatic interaction. The formed ionic complexes not only combine chemical activity of both inorganic and organic components, but also display well-organized structures and enhanced functions. In this context, we summarized the recent progress on the self-assembly and bio-functions of polyoxometalate complexes. As an amphiphilic organic/inorganic hybrid system, the concerned complexes assembling into diverse nanoscaled structures are described, together with their smart response to external temperature, pH, optical and other factors. Furthermore, the synergistically enhanced functions involving catalysis, photochroism, luminescence, and so on, by combining polyoxometalates and surfactants/biomolecules in the complexes, are summarized on the biocompatibility and protection referring to multifunctions such as magnetic, luminescent and photo-thermal transformation properties under bio-conditions. While pointing out the possible difficulties, the encouraging aspects of polyoxometalate based complexes dealing with bio-related applications such as biological imaging contrast agents and therapeutic medicines for antivirus and antifibrillation of proteins have been outlined.

基于有机/无机杂化体的超分子自组装为构建新型纳米结构材料提供了强大的策略。多金属氧酸盐作为一种出色的无机建筑单元已广泛应用于生物相关材料的超分子组装领域，并在胶体和界面化学，纳米材料和医学领域引起了极大的兴趣。聚阴离子簇的表面可以通过静电相互作用被阳离子有机表面活性剂，生物分子和聚合物改性。形成的离子配合物不仅结合了无机和有机组分的化学活性，而且还表现出组织良好的结构和增强的功能。在这种情况下，我们总结了多金属氧酸盐复合物的自组装和生物功能的最新进展。作为两亲性有机/无机杂化体系，描述了组装成各种纳米级结构的有关配合物，以及它们对外部温度，pH，光学和其他因素的灵敏响应。此外，通过在复合物中结合多金属氧酸盐和表面活性剂/生物分子，涉及催化，光致变色，发光等的协同增效功能，归纳了生物相容性和保护作用，涉及多种功能，如磁性，发光和光热转化性质。生物条件。在指出可能的困难的同时，