Mannose‐Decorated Multicomponent Supramolecular Polymers Trigger Effective Uptake into Antigen‐Presenting Cells,ChemBioChem

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Mannose‐Decorated Multicomponent Supramolecular Polymers Trigger Effective Uptake into Antigen‐Presenting Cells
ChemBioChem ( IF 2.6 ) Pub Date : 2018-04-17 , DOI: 10.1002/cbic.201800114
David Straßburger ₁ , Natascha Stergiou ₂ , Moritz Urschbach ₁ , Hajime Yurugi ₃ , Daniel Spitzer ₁ , Dieter Schollmeyer ₁ , Edgar Schmitt ₂ , Pol Besenius ₁

Affiliation

Self‐assembled macrophage targets: A modular route is presented to prepare multifunctional supramolecular polymers based on self‐assembled dendritic peptide amphiphiles decorated with mannosides to effectively target antigen‐presenting cells, such as macrophages. The multicomponent co‐assembly protocol is a powerful platform for the development of fully synthetic multifunctional vaccines.