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Stereolithographic and molding fabrications of hydroxyapatite-polymer gels applicable to bone regeneration materials
Journal of the Taiwan Institute of Chemical Engineers ( IF 5.5 ) Pub Date : 2018-02-27 , DOI: 10.1016/j.jtice.2018.01.034
Mekuriaw A. Kebede , Karen Sabrina Asiku , Toyoko Imae , Masaru Kawakami , Hidemitsu Furukawa , Chang Mou Wu

A bone regeneration material was fabricated from hydroxyapatite-poly(dimethyl acrylamide) (HAp–PDMAAm) composite through stereolithographic 3D printing technique, and additionally, a material from HAp–agarose composite was also prepared inside a mold. Then the tensile strength and morphology of both bone regeneration materials were compared. The HAp–PDMAAm composite xerogel from 0.17 weight ratio of HAp content can resist a tensile stress of 30.2 MPa, whereas 26.2 MPa was observed in case of agarose bone composite 0.5 weight ratio of HAp content. The achieved mechanical strengths indicate that the products can be applicable as bone regenerative medicine and the utilized fabrication technique plays a significant role toward patient-specific bioprinting technology.



中文翻译:

适用于骨再生材料的羟基磷灰石聚合物凝胶的立体光刻和成型加工

骨再生材料是通过立体光刻3D打印技术由羟基磷灰石-聚(二甲基丙烯酰胺)(HAp-PDMAAm)复合材料制成的,此外,还可以在模具内部制备由HAp-琼脂糖复合材料制成的材料。然后比较两种骨再生材料的拉伸强度和形态。HAp含量为0.17重量比的HAp-PDMAAm复合干凝胶可以抵抗30.2 MPa的拉伸应力,而琼脂糖骨复合物的HAp含量为0.5重量比时,观察到26.2 MPa。达到的机械强度表明该产品可以用作骨再生药物,并且所利用的制造技术对患者特定的生物打印技术起着重要的作用。

更新日期:2018-02-27
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