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Microfluidics: Guidance and Self‐Sorting of Active Swimmers: 3D Periodic Arrays Increase Persistence Length of Human Sperm Selecting for the Fittest (Adv. Sci. 2/2018)
Advanced Science ( IF 14.3 ) Pub Date : 2018-02-27 , DOI: 10.1002/advs.201870008
Thiruppathiraja Chinnasamy 1 , James L. Kingsley 2 , Fatih Inci 1 , Paul J. Turek 3 , Mitchell P. Rosen 4 , Barry Behr 5 , Erkan Tüzel 2 , Utkan Demirci 1, 6
Affiliation  

A model‐driven design featuring pillar arrays that efficiently and non‐invasively isolate highly motile and morphological normal sperm, with normal epigenetic global methylation, is presented by Erkan Tüzel, Utkan Demirci, and co‐workers in article number 1700531. The image shows the Simple Periodic ARray for Trapping And isolatioN (SPARTAN) device sorting the unshapely and damaged sperm (in pink) from healthier sperm (blue). The unshapely sperm are diverted by the pillars in the device going in circles and do not emerge from the labrynth of the pillars in the system. In the image, pink and blue colors are used for illustration purposes only and do not denote the presence of an X or Y chromosome.
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中文翻译:

微流控技术:主动游泳者的指导和自我分选:3D周期性阵列增加了人类选择最适体的精子的持久性长度(Adv。Sci。2/2018)

ErkanTüzel,Utkan Demirci和同事在文章编号1700531中提出了一种模型驱动的设计,其特征是具有有效地,无创地分离高活动性和形态正常精子以及正常表观遗传甲基化的柱阵列。用于诱捕和隔离的简单定期阵列(SPARTAN)设备将健康的精子(蓝色)中的畸形和受损的精子(粉红色)分类。畸形的精子会被装置中的柱子绕圈转移,并且不会从系统中柱子的迷宫中出来。在图像中,粉红色和蓝色仅用于说明目的,并不表示存在X或Y染色体。
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更新日期:2018-02-27
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